For NBA 2K22, if you keep the sprint button in your hand or make a lot of dribbles, your stamina will fall off of the cliff 2K MT. It wasn't nearly as significant of a concern last year since you were able to shoot effectively when exhausted. In 2K22 your shot meter will actually reduce as you get tired as well as your release slows. This can make it more difficult to hit shots and gives your opponent more of a possibility to compete.
So, our advice is not to speed up. With stamina, shooting can be much more comfortable this year. You can benefit from this by playing prudently and you'll have success. If you're an offline player, one of the most important tips is to use the advancements in Visual Concepts made to AI aid in defense. Prior to AI, defenders would come at you from picking up their players wide in the air. This made it easier to triple hunt from the sidelines if you had difficulty scoring.
In 2K22, those defenders don't appear to be as crashing making it possible to play an exciting pick-and-roll that feels more like a real NBA game. Now, it's about understanding the defense and making the correct decision. If you call for your center to make a choice and the player shifts to you, throw it at the big guy and let him battle an opponent who is smaller. If they don't switch, congrats on your open lane. Get to the bucket and shoot a layup. You could also be fouled.
To initiate a pick-and-roll simply hold L1 (LB in the case of Xbox) as you point to the player you wish to take to the pick. The key is to be patient. If you're unable to locate the button and don't find the lane you want, don't force it Buy MT 2K22. Try resetting and trying again. Remember, you need to play with a sense of shrewdness and be slow.